Are There Any Side Effects to Taking Creatine?

Is creatine bad for you? A misinterpretation of lab tests may explain concerns over kidney safety with creatine supplementation.

If you missed it, check out the previous video: What Is Creatine? Can It Treat Sarcopenia (Muscle Loss with Age)? (https://nutritionfacts.org/video/what-is-creatine-can-it-treat-sarcopenia).

I first talked about the contamination issue a decade ago in Creatine Brain Fuel Supplementation (https://nutritionfacts.org/video/creatine-brain-fuel-supplementation/).

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71 Risposte a “Are There Any Side Effects to Taking Creatine?”

  1. So does Dr Greger recommend we take creatine or not? Previous videos concluded the risk of adulteration tipped the balance against it. Has that advice changed?

  2. I remember starting and loading on Creatine back in the late 1990's and for a week my biceps almost doubled in size because of water retention. It looked awesome but I had trouble even bending my arms at the elbows because they muscle wouldn't stretch.

  3. I took it in my 20s while working out with no issues but tried it again in my 40s while losing weight with intermittent fasting and suffered from insomnia. Basically, I'd be wide awake by 3:30am no matter what I did which started when I started taking it and lasted until a week after I stopped. I had the same issue with the low/no calorie artificial sweeteners (or even natural ones).

  4. I remember taking it in the 90s and it used to make the glands in my neck swell up and made me feel sick! Tried it again this time creapure from bulk starting about 6 months ago and as a man in my mid fifties is really helping with strength and muscle fatigue. I would say i am about 15% stronger when taking creapure. No percieved side effects this time either.

  5. If you're not using creatine you're doing it wrong, especially vegans. I was the first to write about the non gym benefits of creatine in the print magazines circa mid 90s. Nice to see this and other channels finally starting to catch up…

  6. Side effects: getting monstrously jacked, watching anime rage edits in the gym, developing a caffeine addiction

  7. 5% just seems not worth the non-zero risk- especially taking it for life. Put the same effort into lifting harder. Almost everyone can do that and zero side effects.

  8. As suggested in the video, the side effect I had is that it messed-up my creatinine bloodwork results, alarming my GP. I quit creatine and tested normal 4 weeks later. I'm not comfortable foregoing the creatinine metrics, so I'm staying away from creatine. Age 55 at the time.

  9. I mix 3 g into my protein powder that I take every day. There are too many confounding variables in my life for me to say whether it's had any benefit. I also take a dozen types of dietary supplements in pill form, so I can't really associate cause and effect with any of them. But overall, it seems like a pretty good bet, and cheap compared to things like medical insurance and doctor's bills.

  10. I have gout and I saw a paper saying creatine can increase uric acid levels, did you find this when making this video? I am interested in creatine supplementation but will hold off if it means more gout flareups.

  11. I take Creapure, made in Germany, which essentially eliminates the risk of contaminated creatine. It's pricier but worth the piece of mind for such a great supplement.

  12. Everything I start taking creatine, I get joint pain after a few days. Have tried several different brands, even increased the amount of water I take, but the problem still persists for me with creatine

  13. I had the worst, most painful putbreak of gout I have ever had after being on creatine for a week or so. Threw the rest away.

  14. Something that has mixed evidence and is one hypothesis as to how it can improve muscle mass with exercise is an increase in DHT without an increase in overall testosterone in men, especially with higher doses, which has an effect on different types of prostate cancer. There's anecdotal evidence from many men who supplement with creatine that it can possibly increase the rate of androgenic alopecia, which would at least point in the direction of some change in androgens at larger doses when combined with strength based exercise.

  15. I don't know what it was, but I stopped taking it because it started to give me severe insomnia.
    Haven't taken creatine since. I started taking a natural extract of cordyceps mushrooms instead, it's been great.

  16. What about creatine issues with those that have had cancer? PubMed has several articles 2021/2022 that indicate "enhanced creatine metabolism as a central component of progressive disease". The article is referring to prostrate cancer. There is also the 2021 article about the "Two sides to Creatine", again discussing similar information. I wish Nutrition Facts would check on the safety of supplements mentioned to ensure as significantly as possible that there are no safety issues for All individuals. Thank you.

  17. Could Mr. Greger explain the fuss about creatine and hair loss? I know this only comes from one (2009) study but it amazes me that creatine is one of the most studied supplements and we still have no clear answer about the relationship between creatine and hair loss… Would be so nice to get a video on nutritionfacts about this…

  18. My sons took it while working out and they seemed far more aggressive — not in a good way. I want to see a study that looks at the effect on the amygdala.

  19. Some cooking methods can actually increase the creatine content of food. For example, slow cooking meat in a liquid (sous vide) can increase the creatine content by up to 10%. This is because the low heat and long cooking time can help to break down the connective tissue in the meat, which releases creatine.

  20. Creatine (3.75g/day) made me itch like mad on my back and sides. I saw a comment elsewhere a while ago that said the same thing. So I stopped and 10 days later, no itching. Just to check I started the creatine at reduced levels and after about three weeks, the itching started up again. Itching like this is possibly symptomatic of other effects elsewhere, possibly on organs like the kidneys or liver. So I've stopped supplementing with creatine for good.

  21. I took creatine for 3 months prior to my physical this year. ALT and AST liver enzymes were higher than ever before, out of normal range first time ever. Retested after a month suspecting creatine and low and behold, back to normal. Be careful with supplements.

  22. Regarding quality of Creatine, when I went shopping for what I eventually bought I went to the NSF site and searched for their list of NSF certified suppliers of Creatine. (it was a short list) For Americans who, unlike Germany say, don't have any pharmaceutical standards for ordinary supplements, the NSF is your huckleberry. They assure or certify that the contents are Creatine only. Professional athletes rely on this certification because there are 250 odd substances professional athletes can't have found in their blood. I think for Americans this is the best and only 'certified' source of Creatine. I bought for instance 315g of Creatine Monohydrate from "Klean Athlete" that contains a 5g scoop. I was measuring 2.5g (I have a Tanita mini scale, accurate to two places) and adding this to a meal before a workout. I have now increased that to 3g based on these videos.

  23. from 1-10 – if 1 is toxic, 5.5 is neutral, and 10 is flax/turmeric level – i consider creatine to be like a 6-7 on the health promoting scale
    however on "quality of life" scale i consider it like a 9 or so, just feels like to have more muscle control/be less shacky

  24. I'm glad you are discussing the older adult population and one of the main concerns when they come into long-term care facilities. We are now admitting residents with severe to extreme malnutrition, all associated with sarcopenia. It seems that there is still no "magic pill" to improve their muscle mass quickly. Goos nutrition assessment and team intervention remain the key.

  25. How long does it take for the excess Creatine to be cleared from the body to the extent that it will not impact our lab tests? It is good to hear that I can possibly put Creatine back on my supplementation schedule. It does give me an energy boost during my workouts.

  26. 2:10 if I add the supplement on top of a (very) hot meal, would that pose the threat of creating those carcinogens? …or: what's the allowed temperature? Thanks for the video!

  27. I eat everything. Since I am 65 yrs old. Can't afford all these supplements except I buy Vit D mag+ K+. Also my Creatinine (related to Kidney function) is 1.3, high-normal, so I'm not taking Creatine. Great info, thanks !

  28. After taking creatine for a few weeks, I began to have cramps in my legs at night. Googled it to find that it is a side effect—apparently takes water from cells in the muscle. Stopped taking creatine and the cramping stopped.

  29. My ex tried taking it and he ended up projectile vomiting all over and he was not one to throw up. It was not easy to clean up either.

  30. Does anyone know the risks involved with cycling off creatine? I find the "comedown" particularly bad… brain fog, lethargy, memory loss etc…

  31. This was part two of his videos on the subject. But I'm sorry to say, hardly conclusive. I was hoping given that so many 'experts' recommend it for a more in depth video.

  32. How do you reconcile this with your other videos? Creatine apparently increases IGF-1, which you have scorned in your previous videos.. and you're recommending this?

  33. Supposed clean plant based proteins ruined my health.
    Water buffalo meat, raw milk and creatine have been a game changer. 40 years old and on my way to the best shape of my life!

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