Prodotti finali della glicazione avanzata (AGE) e declino cognitivo

I prodotti finali della glicazione avanzata (AGE) possono essere una spiegazione del motivo per cui coloro che consumano carne possono avere fino a tre volte il rischio di sviluppare la demenza rispetto ai vegetariani.

Il video che ho citato è La migliore dieta per invecchiare in buona salute (https://nutritionfacts.org/video /la-migliore-dieta-per-invecchiare-in-salute). La glicazione è in realtà uno dei percorsi dell'invecchiamento che tratterò nel mio prossimo libro How Not to Age. (Come sempre, tutti i proventi vanno in beneficenza.) Stay tuned!

Per altri video sulla salute del cervello, vedere:
• Cibi salutari per combattere l'invecchiamento (https://nutritionfacts.org/video/brain-healthy-foods-to-fight-aging/)<br/> • Come prevenire l'Alzheimer con la dieta (https://nutritionfacts.org/video/how-to-prevent-alzheimers-with-diet/)
• Il gene dell'Alzheimer: controllo dell'ApoE (
https://nutritionfacts.org/video/the-alzheimers-gene-controlling-apoe/)
• Ridurre l'assunzione di glicotossina per prevenire l'Alzheimer (https://nutritionfacts.org/video/reducing-glycotoxin- assunzione-per-prevenire-l-alzheimer/)

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Grazie per la visione. Spero che ti unirai alla rivoluzione della nutrizione basata sull'evidenza!
-Michael Greger, MD FACLM

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35 Risposte a “Prodotti finali della glicazione avanzata (AGE) e declino cognitivo”

  1. I love how they disregard low carb plants based diets by just measuring the effects of diets with high animal fat consumption.

  2. Perfect timing Dr. G, as people prepare for thanksgiving! Maybe we can get some more plants on the table. Thank you for all your work to provide high quality information to the public without bias ❤

  3. Blah blah blah.. this is great info as well as 100% opposite research and info that shows clearly that low card high fat is the way to go. What do I think? No one knows s..t and this is all BS and fads. I have vegan friends that are sick as hell and obese 24 hours a day as I do meat lovers that are sick as well. And I know heavy eaters and smokers that live to 90 without any health problems. Do and eat whatever you want.. life is too short for any of this that makes no sense and info that is as accurate as any other fad..

  4. Informative as always 🙂 Can't appreciate these videos enough, actually breaking down studies and presenting data. I know you've been doing this for years, but it's quite unique.
    I have to say though that despite animal fat being linked to mental decline and diseases, so many people suffer and even die sooner from heart disease, cancer in their 30s, 40, 50s before they suffer mental diseases. Quite sad really. Even my own mother suffered a heart attack at age 52.
    Then again, my grandfather was 62 when he had full blown Alzheimer's where he couldn't even go the toilet by himself anymore, turned beasically into a toddler, so not that old either.

  5. I love how Dr G. Just presents the facts and lets the viewer make their own opinions. Being whole food plant based already, this video will not change my opinion. And I am not going to look up these studies and read. It is sort of is like a sports highlight real with summary after summary of research findings. I love it when the home team wins. 🎉🎉🎉

  6. One question. I noticed in one of your highlighted studies that the sample size was only 16. Is that enough to make any meaningful universal conclusions? Statistically speaking, it seems pretty skimpy.

  7. I want a study investigating outcomes in vegans eating roasted nuts and panfried tofu/noodles. Is there still enough benefit to ditch those?

  8. What about the fact that vegans have higher AGEs than omnivores? "Advanced glycation end products and nutrition" PMID: 12234125

  9. Regarding the study suggesting high-fat diet impairs cognitive function, they did not specify the type of fat these college students were fed. Could it be that they were fed seed oils. There have been numerous studies associating seed oils with cognitive impairment, especially canola oil. Here is one reference: "Effect of canola oil consumption on memory, synapse and neuropathology in the triple transgenic mouse model of Alzheimer’s disease"

  10. Very informative. Thanks Dr. G. . We can see in the list Pizza, thin crust 6,825 AGE ku/serving which is just after Chicken crispy (McDonald's). I'd like to know if it is only the crust or the whole with the topping? Maybe someone has the answer.

  11. Ketogenic diet is a joke or even worse it's a recipe for health disaster, btw how come dr berg is up and posting videos till now with his Ketogenic diet shyte, his Cognitive still up, I guess he's cheating and eats carbs in order to function, lol

  12. Liking the sound of an SAF test very much! Also, I see that at the time of posting this video the channel is up to 897K subscribers … Phenomenal!

  13. Ironically 99% of people, eat meat for protein linked to improved Brain Function and expansion. This is the most Evil superstition and lie in human history. The human Brain grows and develops fastest before the age of One. What is the best food for a baby ? Human Breast Milk which has the LOWEST % Protein of all Herbivores.

  14. What im interested to know is whether you ever cite studies that do not correlate with your position, which seems to promote a plant based diet. There are some out there that support a sat fat diet. So its ok saying youre not biased but isnt presenting one side of the argument precisely that?

  15. Just a classic example of manipulation with data. I can find more papers saying just the opposite. But in short – no, meat is not the source of AGEs. Only grilled chicken contains poly-methylglyoxal byproduct in the crusty skin, which has been shown not to react with our internal proteins btw, but there more studies should be done about it. Yes, meat (depending on a type and cooking style) may be unhealthy, including heterocyclic aromatic amines (HAA) and PAHs, as well as TMAO (trimethylamine N-oxide), but NOT AGEs. The main source of AGEs are carbs only – glucose and fructose (fructosamine type of AGEs) in particular. Especially fruits, sweets/cakes/candies, sugary sodas, white/milk chocolate, honey, bakery goods are very unhealthy regarding AGEs. Rice, potato, pasta, muesli, non-sweet berries too, but to a lesser extend, due to a lower glucose spikes and ability of cells uptake this low glucose from the blood stream effectively, incorporate and deposit it into glycogen, where it can't react aggressively anymore… So it is about the timing of free monosaccharides floating around. Moreover, carbs heated higher than 120 °C produce acrylamide, and even at lower temperatures (starting from 65 °C) – 5-Hydroxymethylfurfural which is almost not relevant for meat, btw. Frequent consumption of carbs is the major reason of type 2 diabetes, metabolic syndrome and obesity, on global scale. Not protecting meat here, as fatty fried meat leads to increased atherosclerosis, and indeed, to chronic inflammation too, as mentioned in video.

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