Risposta dell'industria delle uova a colina e TMAO

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Pubblicato inAcademy of Nutrition and Dietetics , American Egg Board , animal products , antibiotics , are eggs bad for you , blood pressure , cancer , cholesterol , choline , dairy , dr greger , dr gregor , dr michael greger , egg , eggs , eggs and choline , eggs and TMAO , gut flora , heart disease , heart health , high blood pressure , how not to die , industry , industry influence , kidney disease , kidney health , meat , michael greger , microbiome , mortality , nutrition facts , nutritionfacts.org , plant-based diets , response , stroke , TMAO

In che modo l'industria delle uova ha finanziato uno studio progettato per coprire la reazione tossica dell'ossido di trimetilammina al consumo di uova.

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Purtroppo , questo sembra essere la norma per l'industria delle uova. Per altri loro imbrogli, vedere:
ā€¢ Uova e colesterolo: affermazioni palesemente false e fuorvianti ( http://nutritionfacts.org/video/eggs- e-colesterolo-dichiarazioni-patentemente-false e fuorvianti/)
ā€¢ Chi dice che le uova non sono sane o sicure? (http://nutritionfacts.org/video/who-says-eggs-arent-healthy-or-safe/)<br/> ā€¢ Sfatare i miti dell'industria delle uova (http://nutritionfacts.org/video/debunking-egg-industry-myths/)
ā€¢ Uova e funzione arteriosa (http://nutritionfacts.org/video/eggs-and-arterial-function/ )
ā€¢ In che modo la Egg Board progetta studi fuorvianti (http://nutritionfacts.org /video/how-the-egg-board-designs-misleading-studies)

Per informazioni sullo sviluppo della storia del TMAO , vedi Carnitina, colina, cancro e colesterolo: The TMAO Connection ( http://nutritionfacts.org/video/carnitine-choline-cancer-and-cholesterol -the-tmao-connection/).

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100 Risposte a “Risposta dell'industria delle uova a colina e TMAO”

  5. I don't get it though, if your liver could remove the TMAO is half a day, then why does it matter if you eat eggs? Does this only work in the short-term, and in the long term your liver won't be able to remove the TMAO, or what?

  8. The problem is not choline itself. Although choline is the starting material for the production of TMAO, the real villains are carnitine and the TMAO-producing bacteria associated with meat-eating. Many plant foods (e.g., soy beans and broccoli) contain almost as much choline as eggs, yet because the microbiome of 100% plant-eaters contains a different profile of bacteria, we do not see high levels of TMAO in this population.

  16. From what I've read, and according to the movie "The Widow Maker," the best indicator of risk of a pending heart attack is a Coronary Calcium Score. So, if there's a simple, cheap metabolite test that can screen for calcium accumulation in the arteries, I think that would be the magic test. Incidentally, vitamin K2 is what directs arterial calcium to its proper place in our bodies, our bones and teeth. For vegans, that would mean consuming natto, fermented soy.

  18. I think there's more to it…

    1. The original study showing diet increases postprandial TMAO in humans used 2 eggs (4:34), whereas the egg study Dr Greger references at the end (5:19) only used 6 egg/wk and measured fasting TMAO. A more recent study showed that it takes a meal of 2 or more egg yolks to significantly increase postprandial TMAO, with a peak at 8hrs.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135488/
    So the egg board study would fail to pick up TMAO changes on two counts – not enough eggs and fasting measurements.

    2. Gut microbiota influences the ability of egg/beef to increase TMAO. However, fish contains preformed TMAO, and a meal of cod fillet increased blood levels around 50 times more than eggs/beef!
    https://www.ncbi.nlm.nih.gov/pubmed/27377678
    Yet a review of the current evidence (mostly observational studies) shows fish consumption is associated with lower risk of CVD?!
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705336/
    Interestingly, in animal models, fish protein increases TMAO and promotes CVD.
    https://www.ncbi.nlm.nih.gov/pubmed/26502377
    However, fish oil protects against metabolic effects of TMAO, and therefore perhaps other things?
    https://www.ncbi.nlm.nih.gov/pubmed/25686243

    3. The difference between postprandial and fasting TMAO may be important. The diet studies show you can increase postprandial TMAO, but the metabolomic studies show that fasting TMAO predicts CVD.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086762/
    Since the body can normally clear TMAO fairly well, elevated fasting TMAO might suggest clearance/kidney problems.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127123/
    Note, fasting TMAO was still lower in vegans and vegetarians than omnivores.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650111/

    4. Other dietary factors have also been shown to modulate blood TMAO.
    High-fat meals increase postprandial TMAO.
    https://www.ncbi.nlm.nih.gov/pubmed/?term=high+fat+diet+tmao
    Whereas fruit (apple sauce) decreased postprandial TMAO.
    https://www.ncbi.nlm.nih.gov/pubmed/27377678

    So does diet regulate more than just microbial TMA production, perhaps also endogenous TMA oxidation (FMO3), TMAO clearance and TMAO pathogenicity?

  19. Holy cow! This was disturbing and convincing all at the same time. We love eggs. Giving up Huevos Rancheros is going to be very difficult.

  22. Uhh, honestly is there any shadier industries than the meat, dairy egg ones? Maybe sugar. But what a joke they are. I can hardly wait for the day when the masses know the truth. Goodbye liars

  24. Big headline this morning on MSN…"Eating an egg a day can stop you from getting a stroke".Ā  The unnamed study MSN referred to was published in the Journal of the American College of Nutrition. I'd sure like to hear more details about the study.

  27. wow! Thank you so much for all of the amazing knowledge you share with us!!!

    I have a 6month old and I'm being pressured by her pediatrician to give her blended steak for iron!!! I exclusively breastfeed. Do you have any insight I could share with my pediatrician to help her be more open minded to the idea of a vegan baby??!!

  30. Thank you for this one. I really like how you showed the way the egg industry rigged their results. Keep up the great work. I've already bought your book for four people! It also turned my boyfriend Whole food Vegan!

  35. An explanation of why the reduction of TMAO levels after that period by the kidneys didn't alleviate the effects would have been helpful.

  36. Now that makes way more sense than the cholesterol talking that I see spread around vegan's channels. This would match the fact that okinawas consume meat once or twice a month with no impact on their health cause their gut bacteria just ignores the L-carnitine and Choline.

  37. I have consumed eggs in abundance for past 53 years. Just had full heart MRI, guess what, perfect cardio vascular health. No furring, no arterial damage, nada, nout, zilch……….

  38. Choline is an essential nutrient though, TMAO or no TMAO. We need it. Just font get it from meat dairy or eggs. If the sources of choline from plant foods give us TMAO, so be it. We need choline.

  41. Dr. Greger, thank you so much for FINALLY allowing people to access information about how to stay healthy by eating healthy! The food industry, mainly meat, egg, and dairy industries have been allowed to spread false and misleading information that is killing people every day. Your videos are so easy to watch and understand — you take a complex subject and make it easy to understand. All people who care about their health owe you a huge debt of gratitude!

  46. WRONG
    In the study at 3:05 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086762/) they measured fasting plasma levels of TMAO
    "Fasting plasma levels of TMAO, choline and betaine were quantified by LC/MS/MS using methods specific for each analyte (Supplementary Fig. 8)"
    If carnivores have normal TMAO in fasted state like you are acknowledging at 5:13, this proves nothing. Take this video down it is misleading information.

  47. But if it goes back down after 12 hours, then wouldn't that mean they don't have high TMAO levels? Its seems to me more misleading to do the tests right after consumption.

  48. Dr greger do not join the vegan cult, provide accurate health information, you do not have to go against any non vegetarian for just for the heck of it

  50. Oh, Ok. So it looks like LDL wasnt the cause after all so now were on to new initials like TMAO and new medications. Cant wait to try some. Hope they're not as deadly as those statins.

  56. So no long term effects of eating eggs? TMAO levels drop down to baseline? Good. I think I will still eat eggs in addition to my plant based diet, so I can get enough choline to think. Thanks.

  59. This is no.1 bullshit. This is a propaganda by the supplement industry, where in you have to rely heavily on supplements for the lack of omega 3 and vitamin D3 and Vitamin B12. Don't buy this guy's assumptions

  63. Is choline not involved in removing ammonia from the body. Also research in Amsterdam showed people with OPS (painters disease) had low levels of choline in their brains.

  67. Considering Choline deficiency appears to be a significant risk factor for dementia in vegetarians (and a lot of omnivores as well) I'm curious if there is any way to test if taking choline supplements (not eggs, etc.) on a vegan/vegetarian diet (assuming the gut bugs have adapted to not produce TMA) would cause TMA production? Otherwise, we have a bit of a nutritional Catch-22 Here's a background article – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213596/

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  97. those in the comments saying after 12hrs TMAO is cleared from their body so it is ok to eat eggs , didn't you hear all animal products do raise TMAO levels so eat breakfast and fast for 12 hrs think people it is not that hard

  99. So does this mean that the harmful effects are transitory and only last a little while or is there a cumulative effect that causes the increased risk to remain high?

  100. What about more recent studies that say eggs might not raise TMAO much, whereas supplements do raise TMAO and may not be bioavailable?

    Dietary Choline Supplements, but Not Eggs, Raise Fasting TMAO Levels in Participants with Normal Renal Function: A Randomized Clinical Trial.

    Intake of up to 3 Eggs/Day Increases HDL Cholesterol and Plasma Choline While Plasma Trimethylamine-N-oxide is Unchanged in a Healthy Population.

    Effects of Egg Consumption and Choline Supplementation on Plasma Choline and Trimethylamine-N-Oxide in a Young Population

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