The Pros and Cons of Testing PSA Levels for Prostate Cancer

Given the clear harms and the small and uncertain benefits, most men would presumably decide to decline PSA testing if they knew all the facts, but that’s up to each man to decide.

If you do get diagnosed with prostate cancer, what can you do with diet in addition to whichever other therapies you might choose? See:
• Prostate Cancer Survival: The A/V Ratio (https://nutritionfacts.org/video/prostate-cancer-survival-the-av-ratio/)
• Cancer Reversal Through Diet (https://nutritionfacts.org/video/cancer-reversal-through-diet/)
• Changing a Man’s Diet After a Prostate Cancer Diagnosis (https://nutritionfacts.org/video/changing-mans-diet-prostate-cancer-diagnosis/)<br />• Treating Advanced Prostate Cancer with Diet: Part 1 (https://nutritionfacts.org/video/treating-advanced-prostate-cancer-with-diet-part-1/)
• Treating Advanced Prostate Cancer with Diet: Part 2 (https://nutritionfacts.org/video/treating-advanced-prostate-cancer-with-diet-part-2/)

I detailed the issues with mammograms in my 14-video series, starting with 9 out of 10 Women Misinformed About Mammograms (https://nutritionfacts.org/video/9-out-of-10-women-misinformed-about-mammograms/) and ending with The Pros and Cons of Mammograms (https://nutritionfacts.org/video/the-pros-and-cons-of-mammograms/).

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Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM

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53 Risposte a “The Pros and Cons of Testing PSA Levels for Prostate Cancer”

  1. READ THIS: If PSA is high, next step is the "4Kscore" test – another easy blood test. Most doctors (like the one in this video) don't know about this newer "4Kscore" test so you have to research it yourself and tell your doctor about it.

  2. I had slightly increased PSA at the age of 48 values between 4-5.5 went WFPB and stopped drinking coffee, which made a difference, now 5 years later my values are constantly below 1.0…..

  3. In the U.K. you get the digital examination up the rear end, a psa test, then biopsy. Treatments range from radical prostate surgery, radiation, to hormone therapy and now focal treatments such as nanoknife, ultrasound, and cryotherapy. Survival rate in the U.K. is 95%. It’s alleged that the 5% are those that are diagnosed too late when its become metastatic.

  4. Say what you want, it saved my life. Just a blood test you don't have to do anything else unless you choose to. Hopefully pursue more than one opinion as well.

  5. 16 years ago, I had an elevated psa reading of 13. I ignored it. Then 6 years later, I had a reading of 33. I had the biopsy showing a gleason score of 7 to 8. This all happened 10 years ago. I decided on the "robot" style prostectomy. My removed prostate was lab examined and found to be 65% cancerous. Today I have almost no aftereffects from the surgery. Amongst my friends, 4 of them have died from prostate cancer. I personally advise to get a psa test.

  6. Wow. I have been recommending PSA screening to my primary care patients as I have been taught to do. Thank you, Dr G. I will now change that to a discussion of risks and benefits.

  7. Biopsing prostate cancer, aka poking holes in the capsule, seems like a great way to get cancer to Metastasize, aka spread. Are there any stats on this?

  8. This is the internet. Unfortunately, I'm skeptical that the "get tested — it saved my life" comments here aren't even from real people, but from those with a medical industry agenda.

  9. I think logic dictates that you should get the blood test screening, but hold off on the biopsy until you get more evidence of cancer. NEVER forgo the blood test as its only an eye into ur problem. But the biopsy is the problem not the screening blood test. 😊

  10. It runs in my family (according to 23andme, and the fact that the older generation all had it), and my father's life was probably saved by a PSA test. Zero side effects post surgery. Biopsy showed it was an aggressive type but never came out of the prostate.

  11. This business of treating these decisions like a statistics problem condemns to death people like me whose lives can be saved by PSA screening, followed by biopsy to determine that the discovered cancer is aggressive and needs to be treated. The same nonsensical arguments are used by some people to advise against routine mammograms. My life was saved by a PSA test. Apparently from the statistical argument my life wasn't worth saving.

  12. From my own experience, MRI screening before any biopsy would be better.. …unnecessary biopsies are too common … and if cancer is throughout the prostate, biopsies can cause leakage, I.e. metastases…

  13. Nah thanks! I’m sure a urologist would disagree. Next thing are you going to say to skip colonoscopy? You already told women to skip mammo’s. If I had done what you suggested I would have prob had stage 2 cancer by now. My friend did what you had suggested and that test never picked up her very aggressive cancer! She ended up having to do chemo and then treated for HER! She eats stupid healthy too, not fully plant based though, I bet you guys will blame that too! Yeah this for me is very irresponsible! If I were in my 20’s I would listen to some of the bs you are suggesting! Most men don’t like going to the doctors to begin with, never mind getting their prostate checked and now it’s just a simple blood test for them! Saying something dangerous such as this sort ok’s them not bother getting checked at all. For a doctor this is utterly Irresponsible! Sorry but 😑….

  14. It might interest you to know, that Glasgow University is adding Ivy's cousin, Mebendazole to Docetaxel for PC and it's not for nothing. On another note, City of Hope is adding Ivy to TNBC treatment. Take that as you will.

  15. PSA tests are very easy and so are the biopsies. My friend died of prostate cancer with the "watch and see" situaion. He was only in his mid sixties. Regardless of the studies and recommendations, it's up to you. It used to be the glove treatment and by the time the doctor can feel a tumor, it can be too late.

  16. However, an important detail – sex, or more importantly your amount of sex as a biological male. Males who have a high volume and frequency of sex (alone or in pair) will generally have a low PDA score even if they have early stages of cancer and those who are sexless, can show a high score without any cancer.

  17. Even the inventor of the test no longer recommends it; says it is "little better than flipping a coin". Dr. Mercola adds that a subsequent biopsy (based on PSA) can be very damaging to a man's health. But most doctors still recommend the test. They should be wholly ignored; this is best left as an individual choice.

  18. I read “The Great Prostate Hoax: How Big Medicine Hijacked the PSA Test and Caused a Public Health Disaster” by Richard J. Ablin. Ablin DISCOVERED the Prostate-Specific Antigen yet he railed against its use as a screening test. This video actually sounds like a brief synopsis of his book.

  19. I am a Urologist and psa testing and treatment have evolved. There is less screening for older patients and some with prostate cancer are watched and not treated unless there are signs of aggression. One can die of prostate cancer, and there are huge differences in the high grade vs low grade disease. I tell them all to avoid dairy and consider a plant based diet.

  20. 70 yr old male here. I was diagnosed with PC (Gleason 7) last year, had SBRT (5 radiation treatments in 10 days), with no residual issues. PC treatment has evolved. No longer are they recommending treatment for Gleason 6, which is 50% of those diagnosed. Certain groups have a higher likelihood of PC, including factors such as family history, African American, etc. I have known three men who have died from PC, and none of them were tested, and by time it was discovered, it was too late. Cheers!

  21. This is dated. It's not simply a case of elevated PSA, it's how elevated and how fast. Sometimes it's elevated due to prostatitis or other issues which can be managed. If these treatments don't result in improved then an MRI is scheduled to look lesions, if any. Only after lesions are seen on an MRI are biopsies performed. My BFF just went thru prostate cancer treatment, his brother died of prostate cancer 20 years ago. My other BFF has severe BPH and it's been quite a journey over the last 15 years and we've seen how monitoring and treatment standards have evolved. But the new standard is MRI before any biopsies.

  22. I think this is one of your most important videos, Dr. Gregor. Every man and woman should view it before making a decision on mammography or PSA testing. In the absence of a FULL explanation of risks and benefits, and a discussion of absolute risk reduction, we are NOT making informed decisions.

    The American Academy of Family Physicians recommends against both PSA tests AND digital rectal exams? (1:50) I didn't know this. As I explain below, I debated long and hard regarding the risks and benefits of PSA testing, went ahead, didn't like the results and successfully lowered my number entirely via dietary changes. For me, it was a good-news story. For a close friend, it wasn't: he endured multiple biopsies, radiation, chemotherapy only to be told by his doctor that the cancer was indolent and should have been left alone. Now he suffers from fecal incontinence.

  23. Thank you for this heads up, as this is very serendipitous as I just got a doctor that wants me to get a PSA. I eat a Vegan diet and I'm only 48, and it seems odd she wants me to get a test for something that I'm not at especially high risk for. I was unaware of the risks of over-medicalizing prostate cancer. But I've experienced over-treatment in the past from a neurologist, and I don't want to go down that route again.

  24. Prostate cancer treatment guidelines have been changing. I think most PCPs do PSA screening after a certain age. I was diagnosed with Gleason 6 and doing active surveillance but several friends had aggressive cancer. I'm pretty sure they're glad they were screened. Hopefully, cancer research will lead to a better understanding and treatments.

  25. I'm always surprised by how many people don't seem to understand that profit-driven Western medicine is generally a hammer in search of a nail. Breast cancer screenings have also become vastly overused, to the point where the lifetime radiation exposure and false positives are causing harm that negates early detection benefits.

  26. So far I haven't found anything better drinking than copious amounts of a mix of six or more dark leafy green vegetables, steamed and blended with water (like apple sauce) three times a day, for excellent recovery, bar none. But it must not be a one-time thing. It's astounding how effective this is over time. And for anyone claiming how bitter it can taste, just add honey to the mixture and warm it a bit before drinking; it just works wonders for your health.

  27. Brilliant – and shows all that money spent on healthcare is counterproductive & even kills or seriously injures. Great analysis of the facts & history & how the public are better not doing anything – in many ways, as you showed so elegantly. Thank you. 👍

  28. This video ignores the more recent advances in PSA testing. I'm referring to PSA Velocity & PSA Density. I'm told these metrics can give a better indication of who would genuinely benefit from prostate cancer treatment & who would not.

  29. If you’re African American, disregard this video since we are 4 times more likely to test positive for PC. Diet and lifestyle are the most likely reasons

  30. The other consideration to the cancer data is that they are based on large populations and with probably 90% of people making poor lifestyle choices and 75% of the population being overweight or obese (I am assuming that men and women are pretty close to 3/4 being overweight or obese), that the risk for those that don't drink or smoke, add exercise to their lives and eat lots of whole plant foods (or entirely a whole plant diet) are at much MUCH lower risk than the numbers found in the studies that have been done regarding this cancer and risk.

  31. Thank goodness my father got his PSA tested when his first cousin was dying OF prostate cancer in his early 70s.
    Seems that they both had that ASHKENAZI gene linked to greater risk of prostate cancer.
    My Pop's PSA at 66 was 11 !
    No operation was needed. He was treated with radiation to shrink his 3 tumors.
    A year later, he had radiation proctitis bleeding. NJ proctologist (a true A-hole doctor) told my father, "Good news and bad news. Good news: It won't kill you. Bad news: You'll have to live with it." (I was with my father at that appointment.)
    When we got to the parking lot, I told my father: "You're going to Florida. Call 3 proctologists there — they've seen tons of A-holes. If they don't say that they can stop it, I'll come down with my curling iron and I'll cauterize it for you!"
    First office he called, the receptionist said, "Oh, yes, radiation proctitis, very common. Seven to 10 laser treatments and you'll be fine."
    He called me to ask if he should bother to call any other proctologists. 😂
    I told him: "No. If the receptionist knows the procedure, the doctor is a specialist at it."
    Anyway … 11 years later, after his wife died from colon cancer, his PSA was down to 7.4 at the age of 76.
    That's when I took over the food shopping and meal prep. Having learned the dietary relation to her colon cancer, I turned his diet to 90-95% plant-based. He preferred almond milk with his Cheerios to the "blue water" [skim milk] he previously used. He never knew that meatloaf and meatballs I made were mostly smashed beans. He was no wiser about it, but all the healthier for it.
    By 85, his PSA as down to 4.3!

    If he hadn't had his PSA checked, would he have died from prostate cancer like his cousin? Most likely.
    So, suggesting that one shouldn't get the damned blood test is irresponsible.

    "To save one life is as if to save the world entire."

  32. This analyisis is out of date and as the wife of a Stage 4 prostate cancer victim who would be dead now without PSA screening, I cannot state strongly enough that this video is sloppy and dangerous. It is utterly illogical to state that screening is the problem. Screening does not and cannot create overdiagnosis. Doctors who don't do their homework are responsible for that, not a blood test. Screening saves lives. Dr. Greger, I have read your first book and respect your work on diet and health but please stick to your area of expertise.

  33. My PSA was slowly rising through out my 40’s topping out at 6.35 at age 52, I went to 2 different urologists who screamed at me there was no way to lower the PSA and that I needed a biopsy! FF 2 years doing low carb and fasting it was 3.0, last year at 57 years young it was 2.9! I asked my doctor how this could be, she ran out of the examination room!

  34. This is a very disappointing video. As others have noted, the information is out of date. Also, Dr. Greger, like myself is one of those who would benefit most from testing and treatment because due to our healthy lifestyles our longevity is considerably greater than average, and we might well die from prostate cancer rather than WITH prostate cancer. I have known 4 men who died of prostate cancer. Earlier treatment might have saved them.
    Due to a PSA of 7 I had an MRI which showed nothing. But my urologist still wanted to do a biopsy which showed Gleason 6 which many think should not even be called cancer. My next MRI still showed nothing. My urologist wanted to do another biopsy. Instead I will opt for a urine test called ExoDx and perhaps alternate that with the 4 score blood test mentioned below. Along with periodic MRIs. If none of those show concern there's no reason for a biopsy. Note that biopsies done these days should be should be transperineal, i.e. between the rectum and the scrotum, not transrectal which has a greater chance of infection. But they are still not risk-free. And I know from experience they aren't fun. There's an excellent forum I would refer everyone to regarding all of this. Don't give your urologist Carte Blanc. This is just one post:

    https://www.inspire.com/groups/zero-prostate-cancer/discussion/active-surveillance-vs-other-non-surgical-methods/?source=email&utm_source=email&utm_medium=AS&utm_campaign=AS&utm_content=2024-03-15&dderh=9b982c6702553ad5bc3522d18f8ebeca

    And an ultrasound is only used during a biopsy if an MRI shows something and then this is called a fusion ultrasound biopsy to help properly locate the cancer. But even this has problems: see the Vitus prostate Institute in Germany for more on this.

    Note that there are also numerous focal therapies that are a better bet than radical prostatectomy or radiation. If necessary I will try the nano knife.

  35. It's just a blood test. This video is misleading. The message is to get the screening but be cautious about biopsies and starting treatment. Glad I got my PSA tested. Symptoms at 52 years old with a PSA of only 4.2. Tested again 6 weeks later at 6.2. Tested again at 2 weeks later at 6.9. Finally did the biopsy, MRI, Bone Scan, and PSMA PET scan. Stage 4b cancer with met to L1 also verified with biopsy. Wish I had been tested sooner. Wish I had a PSA test more regularly. Might have diagnosed before it had metastasized.

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